Influenza A infection and iInvasive pulmonary aspergillosis in the immunocompetent patient.

Abstract

Aspergillus genus were firstly describe by Micheli in 1729 in Florence¹. Actually there are more than 250 species described as a result of the improvement in molecular characterization techniques. A. fumigatus, A. flavus, A. terreus and A. niger are the species with more risk of invasive infection¹. Traditionally, several conditions related to immunocompromised hosts have been considered risk factors of fungal invasive infection (prolonged neutropenia, transplant, inherited immunodeficiency syndromes, immunosuppressant or corticosteroid therapy, hematologic tumors and graft-versus-host disease)^2,3. However, there are increasingly described invasive fungal infections in immunocompetent patients^4-8. Here we present the case of a patient admitted to the ICU with severe Influenza A infection (H1N1 2009 variant) and concomitant invasive pulmonary aspergillosis.