Profilaxis Antibiótica en el Politraumatizado. Guías 2011 elaboradas por los comités de Infectología Crítica y de Trauma de la Sociedad Argentina de Terapia Intensiva (SATI)

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Rosa Reina

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OBJETIVO:Elaborar guías de profilaxis antibiótica (P-ATB) en politraumatizados.

MATERIALES Y MÉTODOS: Sistema GRADE para calidad y fuerza de la evidencia.RESULTADOS:1)P-ATB prequirúrgica, debridamiento amplio:1-A.2)Trauma abdomen sin lesión de víscera hueca, con/sin packing:2-D; con lesión de víscera hueca, con/sin packing, P-ATB hasta 24 hs del posoperatorio 1-A.3)Trauma de cráneo: a)colocación de sensor de PIC:2-D; b)fractura base cráneo: no P-ATB 1-A; c)fractura hundimiento, por arma de fuego, con/sin atricción de partes blandas (P-ATB no previene meningitis, absceso) 2-D. 4)Trauma maxilofacial: a)cerrado: con/sin hemoseno, no P-ATB 1-A; b)penetrante (ruptura de senos, pérdida de piezas dentarias, con/sin laceración de mucosa):P-ATB por 1-día 1-A; c)fractura mandibular: reducción cerrada/abierta: P-ATB posoperatorio 2-D; d)cara sin fractura, lesión de partes blandas:2-D; e)trauma ocular penetrante: P-ATB durante 1-día 2-D. 5)Quemados: a)prevenir sepsis temprana e infección de herida 1-C; b)quemados graves,de alto riesgo,en ARM: prevención de neumonía e infecciones nosocomiales: 2-B; c)quemadura <40%: curación simple, balneoterapia y resecciones de escaras 1-C;d)procedimientos en quemaduras >40%, P-ATB perioperatoria para reducir bacteriemia perioperatoria e infección de la quemadura: 2-C; e)prevenir pérdida de injertos de piel autóloga 2-C. 6)Trauma tórax: a)colocación de drenaje: 2-D; b)aspiración de contenido gástrico: no P-ATB 1-A.7) Trauma pelvis-genitourinario abiertas a vagina/recto y lesión víscera hueca: P-ATB hasta 24 hs del posoperatorio 1-A. 8)Fractura expuesta huesos largos: a)iniciar P-ATB rápidamente 1-A; b)Gustillo I-II:suspender ATB 24 hs luego del cierre de heridas 1-B; c)Gustillo III: continuar ATB por 72 hs luego del trauma y 24 hs posterior al cierre de heridas 1-B. CONCLUSIONES: Pocas indicaciones con fuerte nivel de evidencia para P-ATB

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Reina R. Profilaxis Antibiótica en el Politraumatizado. Guías 2011 elaboradas por los comités de Infectología Crítica y de Trauma de la Sociedad Argentina de Terapia Intensiva (SATI). Rev Arg de Ter Int. [Internet]. 17 de noviembre de 2011 [citado 22 de octubre de 2024];28(4). Disponible en: https://revista.sati.org.ar/index.php/MI/article/view/285
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BIBLIOGRAFÍA

1.         Chambers, H., General principles of antimicrobial therapy. 11° ed. Manual of Pharmacology and Therapeutics., ed. G. Gilman´s. Vol. 42. 2006.

2.         http://www.gradeworkinggroup.org. 2010.

3.         Atkins, D., et al., Grading quality of evidence and strength of recommendations. BMJ, 2004. 328(7454): p. 1490.

4.         Guyatt, G., et al., Grading strength of recommendations and quality of evidence in clinical guidelines: report from an american college of chest physicians task force. Chest, 2006. 129(1): p. 174-81.

5.         Dellinger, R.P., et al., Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med, 2008. 36(1): p. 296-327.

6.         Burke, C., Prophylaxis and Immunizations. 8° ed. Antibiotic Essentials 2011. 338-339.

7.         SADI. Actualización de recomendaciones sobre vacunas. 2010; Available from: www.sadi.org.ar/files/Actualizacionenvacunas_SADI2008.pdf.

8.         CDC.  2010; Available from: http://wwwnc.cdc.gov/travel/yellowbook/2010/chapter-2/tetanus.htm.

9.         Pittet, D., B. Allegranzi, and J. Boyce, The World Health Organization Guidelines on Hand Hygiene in Health Care and their consensus recommendations. Infect Control Hosp Epidemiol, 2009. 30(7): p. 611-22.

10.       Siegel, J.D., et al., 2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings. Am J Infect Control, 2007. 35(10 Suppl 2): p. S65-164.

11.       Lee, I., et al., Systematic review and cost analysis comparing use of chlorhexidine with use of iodine for preoperative skin antisepsis to prevent surgical site infection. Infect Control Hosp Epidemiol, 2010. 31(12): p. 1219-29.

12.       Stevens, D.L., et al., Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis, 2005. 41(10): p. 1373-406.

13.       Petersen, K. and P. Waterman, Prophylaxis and treatment of infections associated with penetrating traumatic injury. Expert Rev Anti Infect Ther, 2011. 9(1): p. 81-96.

14.       Trilla A, M.J., Preoperative antibiotic prophylaxis. 3° ed. Prevention and Control of Nosocomial Infections, ed. W. R. 1997. 867-887.

15.       Morales, C.H., et al., Intra-abdominal infection in patients with abdominal trauma. Arch Surg, 2004. 139(12): p. 1278-85; discussion 1285.

16.       Luchette, F.A., et al., Practice Management Guidelines for Prophylactic Antibiotic Use in Tube Thoracostomy for Traumatic Hemopneumothorax: the EAST Practice Management Guidelines Work Group. Eastern Association for Trauma. J Trauma, 2000. 48(4): p. 753-7.

17.       Morales, C.H., et al., Surgical site infection in abdominal trauma patients: risk prediction and performance of the NNIS and SENIC indexes. Can J Surg, 2011. 54(1): p. 17-24.

18.       Schnuriger, B., et al., Microbiological profile and antimicrobial susceptibility in surgical site infections following hollow viscus injury. J Gastrointest Surg, 2010. 14(8): p. 1304-10.

19.       Velmahos, G.C., et al., Severe trauma is not an excuse for prolonged antibiotic prophylaxis. Arch Surg, 2002. 137(5): p. 537-41; discussion 541-2.

20.       Nicol, A.J., et al., Packing for control of hemorrhage in major liver trauma. World J Surg, 2007. 31(3): p. 569-74.

21.       Korinek, A.M., et al., Risk factors for neurosurgical site infections after craniotomy: a critical reappraisal of antibiotic prophylaxis on 4,578 patients. Br J Neurosurg, 2005. 19(2): p. 155-62.

22.       Bayston, R., et al., Use of antibiotics in penetrating craniocerebral injuries. "Infection in Neurosurgery" Working Party of British Society for Antimicrobial Chemotherapy. Lancet, 2000. 355(9217): p. 1813-7.

23.       Ratilal, B., J. Costa, and C. Sampaio, Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures. Cochrane Database Syst Rev, 2006(1): p. CD004884.

24.       Stoikes, N.F., et al., Impact of intracranial pressure monitor prophylaxis on central nervous system infections and bacterial multi-drug resistance. Surg Infect (Larchmt), 2008. 9(5): p. 503-8.

25.       Kyzas, P.A., Use of antibiotics in the treatment of mandible fractures: a systematic review. J Oral Maxillofac Surg, 2011. 69(4): p. 1129-45.

26.       Andreasen, J.O., et al., A systematic review of prophylactic antibiotics in the surgical treatment of maxillofacial fractures. J Oral Maxillofac Surg, 2006. 64(11): p. 1664-8.

27.       Soheilian, M., et al., Prophylaxis of acute posttraumatic bacterial endophthalmitis: a multicenter, randomized clinical trial of intraocular antibiotic injection, report 2. Arch Ophthalmol, 2007. 125(4): p. 460-5.

28.       Durtschi, M.B., et al., A prospective study of prophylactic penicillin in acutely burned hospitalized patients. J Trauma, 1982. 22(1): p. 11-4.

29.       de La Cal, M.A., et al., Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial. Ann Surg, 2005. 241(3): p. 424-30.

30.       Vindenes, H. and R. Bjerknes, The frequency of bacteremia and fungemia following wound cleaning and excision in patients with large burns. J Trauma, 1993. 35(5): p. 742-9.

31.       Steer, J.A., et al., Randomized placebo-controlled trial of teicoplanin in the antibiotic prophylaxis of infection following manipulation of burn wounds. Br J Surg, 1997. 84(6): p. 848-53.

32.       Mozingo, D.W., et al., Incidence of bacteremia after burn wound manipulation in the early postburn period. J Trauma, 1997. 42(6): p. 1006-10; discussion 1010-1.

33.       Alexander, J.W., et al., Prophylactic antibiotics as an adjunct for skin grafting in clean reconstructive surgery following burn injury. J Trauma, 1982. 22(8): p. 687-90.

34.       Ramos, G., et al., Systemic perioperative antibiotic prophylaxis may improve skin autograft survival in patients with acute burns. J Burn Care Res, 2008. 29(6): p. 917-23.

35.       Maxwell, R.A., et al., Use of presumptive antibiotics following tube thoracostomy for traumatic hemopneumothorax in the prevention of empyema and pneumonia--a multi-center trial. J Trauma, 2004. 57(4): p. 742-8; discussion 748-9.

36.       Sanabria, A., et al., Prophylactic antibiotics in chest trauma: a meta-analysis of high-quality studies. World J Surg, 2006. 30(10): p. 1843-7.

37.       Bochicchio, G.V., et al., Impact of nosocomial infections in trauma: does age make a difference? J Trauma, 2001. 50(4): p. 612-7; discussion 617-9.

38.       Durham, R.M., et al., Multiple organ failure in trauma patients. J Trauma, 2003. 55(4): p. 608-16.

39.       Antonelli, M., et al., Risk factors for early onset pneumonia in trauma patients. Chest, 1994. 105(1): p. 224-8.

40.       Osborn, T.M., et al., Epidemiology of sepsis in patients with traumatic injury. Crit Care Med, 2004. 32(11): p. 2234-40.

41.       The eastern association for the surgery of trauma 2010; Available from: http://www.east.org/tpg/gueval.pdf.

 

 

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