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Palabras clave
Alteraciones endocrinas
Mortalidad
Score
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Resumen
Introducción:
El objetivo del estudio es describir y analizar la función tiroidea en el paciente crítico. Describir si algún patrón se asocia a una mayor mortalidad.
Métodos:
Se analizaron todos los pacientes ingresados en nuestra unidad de cuidados intensivos entre los meses de Enero 2015 y Agosto 2016 y que permanecieron ingresados al menos siete días.
Resultados:
Se incluyeron 242 pacientes. Encontramos diferencias significativas en los valores medios de los índices de gravedad entre los no supervivientes y supervivientes. SOFA (10.45vs7.9); APACHE II (24.42vs20.71); SAPS II (63.14vs50.69). Con respecto a los valores de T3, T4 y TSH, objetivamos diferencias estadísticamente significativas en los valores medios de T3 en el grupo de supervivientes y no supervivientes. 1.5 pg/ml vs 1.15 pg/ml (p=<0.001) IC 95%. (0.224±0.487). No objetivamos diferencias estadísticamente significativas en los valores medios de T4 y TSH. Al realizar el subanálisis según grupo de ingreso, no objetivamos diferencias estadísticamente significativas entre las cifras de TSH, T3 o T4. Si objetivamos diferencias significativas en la mayor parte de los subgrupos en los valores medios de T3.
Conclusiones:
Objetivamos diferencias estadísticamente significativas entre los valores medios de T3 en el grupo de supervivientes y no supervivientes. Los valores de T3 parecen asociarse a la mortalidad. Su descenso no parece asociarse a la enfermedad subyacente sino a la gravedad.
Citas
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