Abstract
Introduction: Recently, different types of vaccines against COVID-19 have been distributed worldwide. Neurological complications, such as acute encephalopathy, have been reported, however it is still speculative whether these complications are accidentally or coincidentally related to the anti COVID-19 vaccine. Two cases of acute encephalopathy are reported after the placement of the 3rd dose of the anti COVID 19 vaccine, messenger RNA (Moderna and Pfizer). In whom meningoencephalitis due to other causes was ruled out. Discussion: the patients were treated empirically with ceftriaxona and acyclovir, without clinical improvement. In both cases, a second LP was performed, which was decisive in the evolution of the patients. Conclusion: health personnel must be attentive to these possible complications. Meanwhile, new research is awaited to establish any association between anti Covid 19 vaccines and neurological complications.
References
2022. Nefrología al día – Sociedad Española de Nefrología.
2. Goss AL, Samudralwar RD, Das RR, Nath A. ANA Investiga: Complicaciones
neurológicas de las vacunas COVID-19. Ana Neurol. 2021;89(5):856-857.
doi:10.1002/ana.26065.
3. M. Karnik, N.M. Beeraka, C.A. Uthaiah, S.M. Nataraj, A.D.S. Bettadapura, G.
Aliev, S.V. Madhunapantula, A review on SARS-CoV-2-induced
neuroinflammation, neurodevelopmental complications, and recent updates on the
vaccine development, Mol. Neurobiol. (2021) 1–29, 4"
https://doi.org/10.1007/s12035-021- 02399-6.
4. P. Perrin, N. Collongues, S. Baloglu, D. Bedo, X. Bassand, T. Lavaux, G.
GautierVargas, N. Keller, S. Kremer, S. Fafi-Kremer, B. Moulin, I. Benotmane, S.
Caillard, Cytokine release syndrome-associated encephalopathy in patients with
COVID-19, Eur. J. Neurol. 28 (2021) 248–258, https://doi.org/10.111/ene.14491.
5. Wu Y, Xu X, Chen Z, et al. Compromiso del sistema nervioso tras la infección por
COVID 19 y otros coronavirus. Brain Immun 2020: 87: 18 -22.
6. Metha P, Mc Auley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. HLH en
colaboración especializada, Reino Unido COVID-19: considera los síndromes de
tormenta de citoquinas y la inmunosupresión. Lancet 2020: 395: 1033-1034.
![Creative Commons License](http://i.creativecommons.org/l/by-sa/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Copyright (c) 2022 Pablo Almada, Rodolfo Eduardo Buffa, Horacio Pignata, Yanina Vernetti