Influenza A infection and iInvasive pulmonary aspergillosis in the immunocompetent patient.
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Published:
Jun 22, 2021
Keywords:
Influenza A, Invasive pulmonary aspergillosis, Immunocompetent host
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Abstract
Aspergillus genus were firstly describe by Micheli in 1729 in Florence1. Actually there are more than 250 species described as a result of the improvement in molecular characterization techniques. A. fumigatus, A. flavus, A. terreus and A. niger are the species with more risk of invasive infection1. Traditionally, several conditions related to immunocompromised hosts have been considered risk factors of fungal invasive infection (prolonged neutropenia, transplant, inherited immunodeficiency syndromes, immunosuppressant or corticosteroid therapy, hematologic tumors and graft-versus-host disease)2,3. However, there are increasingly described invasive fungal infections in immunocompetent patients4-8. Here we present the case of a patient admitted to the ICU with severe Influenza A infection (H1N1 2009 variant) and concomitant invasive pulmonary aspergillosis.
Article Details
How to Cite
1.
Cherchi MS. Influenza A infection and iInvasive pulmonary aspergillosis in the immunocompetent patient. Rev Arg de Ter Int. [Internet]. 2021 Jun. 22 [cited 2024 Dec. 21];38. Available from: https://revista.sati.org.ar/index.php/MI/article/view/730
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Section
Clinical Notes / Case Report
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References
1. Patterson TF. Cap. 259: Género Aspergillus. En: Mandell, Douglas y Bennett. Enfermedades infecciosas. Principios y práctica. 8ª Ed. Barcelona: Elsevier; 2016. p. 3059-73
2. Patterson TF, Thompson GR, et al. Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2016;63(4):e1-60
3. Donnelly JP, Chen SC, et al. Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. Clinical Infectious Diseases 2019. [Epub ahead of print]
4. Shah MM, Hsiao EI, et al. Invasive pulmonary aspergillosis and influenza co-infection in immunocompetent hosts: case reports and review of the literature. Diagnostic Microbiology and Infectious Diseases 2018; 91(2): 147-152
5. Saint-Léger P. Aspergillose pulmonaire invasive chez le patient immunocompétent grippé. Médecine et Maladies Infectieuses 2018, https://doi.org/10.1016/j.medmal.2019.01.004
6. Schauwvlieghe AFAD, Rijnders BJA, et al. Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study. Lancet Respiratory Medicine 2018; 6:782-92
7. Martin-Loeches I, Schultz MJ, et al. Increased incidence of co-infection in critically ill patients with influenza. Intensive Care Medicine 2017; 43: 48-58
8. Crum-Cianflone NF. Invasive aspergillosis associated with severe influenza infections. Open Forum Infectious Diseases 2016; 3(3): ofw171
9. Blot SI, Taccone FS, et al. A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients. American Journal Respiratory Critical Care Medicine 2012; 186: 56-64
10. Bassetti M, Righi E, et al. How to manage aspergillosis in non-neutropenic intensive care unit patients. Critical Care 2014; 18:458-70
11. Tunnicliffe G, Schomberg L, et al. Airway and parenchymal manifestations of pulmonary aspergillosis. Respiratory Medicine 2013; 107: 1113-23
12. Jenks JD, Salzer HJ, Hoenigl M. Improving the rates of Aspergillus detection: an updated on current diagnostic strategies. Expert Review of Anti-infective Therapy 2019; 17(1): 39-50
13. Hage CA, Carmona EM, et al. Microbiological laboratory testing in the diagnosis of fungal infections in pulmonary and critical care practice. An Official American Thoracic Society Clinical Practice Guideline. American Journal Respiratory Critical Care Medicine 2019; 200(5): 535-50
14. Carey IM, Critchley JA, et al. Risk of infection in Type 1 and Type 2 diabetes compared with the general population: A matched cohort study. Diabetes Care 2018; 41(3): 513-21
15. Critchley JA, Carey IM, et al. Glycemic control and risk of infections among people with type 1 or type 2 diabetes in a large care cohort study. Diabetes Care 2018; 41(10): 2127-35
16. García-Vidal C, Arman M, et al. Invasive aspergillosis complicating pandemic Influenza A (H1N1) infection in severely immunocompromised patients. Clinical Infectious Diseases 2011; 53(6):e16
17. Martin-Loeches I, Lemiale V, et al. Influenza and associated co-infections in critically ill immunosuppressed patients. Critical Care 2019; 23: 152-62
18. García-Vidal C, Royo-Cebrecos C, et al. Environmental variables associated with an increased risk of invasive aspergillosis. Clinical Microbiology and Infection 2014; 20(11):O939-O45
19. García-Vidal C, Viasus D, Carratalà J. Pathogenesis of invasive fungal infections. Current Opinion Infectious Diseases 2013; 26(3): 270-6
2. Patterson TF, Thompson GR, et al. Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2016;63(4):e1-60
3. Donnelly JP, Chen SC, et al. Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. Clinical Infectious Diseases 2019. [Epub ahead of print]
4. Shah MM, Hsiao EI, et al. Invasive pulmonary aspergillosis and influenza co-infection in immunocompetent hosts: case reports and review of the literature. Diagnostic Microbiology and Infectious Diseases 2018; 91(2): 147-152
5. Saint-Léger P. Aspergillose pulmonaire invasive chez le patient immunocompétent grippé. Médecine et Maladies Infectieuses 2018, https://doi.org/10.1016/j.medmal.2019.01.004
6. Schauwvlieghe AFAD, Rijnders BJA, et al. Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study. Lancet Respiratory Medicine 2018; 6:782-92
7. Martin-Loeches I, Schultz MJ, et al. Increased incidence of co-infection in critically ill patients with influenza. Intensive Care Medicine 2017; 43: 48-58
8. Crum-Cianflone NF. Invasive aspergillosis associated with severe influenza infections. Open Forum Infectious Diseases 2016; 3(3): ofw171
9. Blot SI, Taccone FS, et al. A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients. American Journal Respiratory Critical Care Medicine 2012; 186: 56-64
10. Bassetti M, Righi E, et al. How to manage aspergillosis in non-neutropenic intensive care unit patients. Critical Care 2014; 18:458-70
11. Tunnicliffe G, Schomberg L, et al. Airway and parenchymal manifestations of pulmonary aspergillosis. Respiratory Medicine 2013; 107: 1113-23
12. Jenks JD, Salzer HJ, Hoenigl M. Improving the rates of Aspergillus detection: an updated on current diagnostic strategies. Expert Review of Anti-infective Therapy 2019; 17(1): 39-50
13. Hage CA, Carmona EM, et al. Microbiological laboratory testing in the diagnosis of fungal infections in pulmonary and critical care practice. An Official American Thoracic Society Clinical Practice Guideline. American Journal Respiratory Critical Care Medicine 2019; 200(5): 535-50
14. Carey IM, Critchley JA, et al. Risk of infection in Type 1 and Type 2 diabetes compared with the general population: A matched cohort study. Diabetes Care 2018; 41(3): 513-21
15. Critchley JA, Carey IM, et al. Glycemic control and risk of infections among people with type 1 or type 2 diabetes in a large care cohort study. Diabetes Care 2018; 41(10): 2127-35
16. García-Vidal C, Arman M, et al. Invasive aspergillosis complicating pandemic Influenza A (H1N1) infection in severely immunocompromised patients. Clinical Infectious Diseases 2011; 53(6):e16
17. Martin-Loeches I, Lemiale V, et al. Influenza and associated co-infections in critically ill immunosuppressed patients. Critical Care 2019; 23: 152-62
18. García-Vidal C, Royo-Cebrecos C, et al. Environmental variables associated with an increased risk of invasive aspergillosis. Clinical Microbiology and Infection 2014; 20(11):O939-O45
19. García-Vidal C, Viasus D, Carratalà J. Pathogenesis of invasive fungal infections. Current Opinion Infectious Diseases 2013; 26(3): 270-6