Brugada-Like pattern secondary to intoxication by tricyclic antidepressants; an unusual presentation.
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Keywords

Brugada
antidepressants
tryciclics
amitriptyline
Poisoning
Arrithmias

How to Cite

1.
Martínez JP, Orejas A, Fong F, Moreno E, Puente T, Diaz R. Brugada-Like pattern secondary to intoxication by tricyclic antidepressants; an unusual presentation. Rev Arg de Ter Int. [Internet]. 2023 Jun. 26 [cited 2024 Jul. 3];40(junio). Available from: https://revista.sati.org.ar/index.php/MI/article/view/868

Abstract

Brugada Syndrome is a channelopathy that caused its carrier an increased risk of ventricular arrhythmias and sudden death. The usual treatment is the implantation of an automatic defibrillator in case of having suffered an arrhythmic event or presenting a family history of sudden death. In some situations it is possible to see a Brugada pattern on the electrocardiogram without the patient suffering from this condition. One of these situations is poisoning with antidepressants or neuroleptics. In this way, it is possible to observe electrocardiograms suggestive of Brugada in these patients without their having an increased risk of arrhythmias. Knowing this phenomenon is of great importance since it prevents physicians from taking unnecessary therapeutic attitudes and poses a greater risk to patients.

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References

A. Bayés de Luna, J. Brugada, A. Baranchuk, M. Borggrefe, G. Breithardt, D. Goldwasser, et al. Current electrocardiographic criteria for diagnosis of Brugada pattern: A consensus report. J Electrocardiol, 45 (2012), pp. 433-442 http://dx.doi.org/10.1016/j.jelectrocard.2012.06.004

D.D. Anselm, A. Baranchuk. Brugada phenocopy: Redefinition and updated classification. Am J Cardiol, 111 (2013), pp. 453 http://dx.doi.org/10.1016/j.amjcard.2012.09.005

R. Rodrigues, P. Amador, L. Rassi, F. Seixo, L. Parreira, N. Fonseca, et al. Brugada pattern in a patient medicated with lamotrigine. Rev Port Cardiol, 32 (2013), pp. 807-810 http://dx.doi.org/10.1016/j.repc.2013.01.009

Fernández-Anguita MJ, et al. Patrón de Brugada en paciente tratada con amitriptilina. Neuro- logía. 2017. https://doi.org/10.1016/j.nrl.2017.11.003

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