Utilidad de las troponinas para el manejo del paciente crítico con enfermedad no cardíaca en la Unidad de Cuidados Intensivo. Revisión narrativa
Barra lateral del artículo
Publicado:
nov 10, 2020
Palabras clave:
Troponinas, Cuidados Criticos, Enfermedad Pulmonar Obstructiva Crónica, Embolia de Pulmon, ACV Isquémico, Insuficiencia Renal Crónica, COVID-19
Contenido principal del artículo
Resumen
Las troponinas cardíacas I y T son componentes del aparato contráctil del miocito y se expresan casi exclusivamente en el corazón. Aunque los valores elevados de troponinas reflejan un daño miocárdico, no indican cuáles son los mecanismos fisiopatológicos involucrados. La elevación de troponina es sinónimo de lesión miocárdica secundaria a 1) aterosclerosis de la arteria coronaria y sus complicaciones que llevan al infarto de miocardio tipo 1; 2) un desequilibrio entre el aporte y la demanda de oxígeno al miocardio lo que produce el infarto tipo 2 y 3) una lesión miocárdica en el contexto clínico de enfermedades cardíacas y no cardíacas. La insuficiencia renal crónica, la lesión cerebral, la sepsis y la lesión pulmonar son algunos cuadros no cardíacos que cursan con lesión miocárdica. El objetivo de esta revisión narrativa es presentar y ordenar la evidencia disponible sobre el comportamiento y la utilidad de las troponinas cardíacas en diferentes entidades clínicas prevalentes en la Unidad de Cuidados Intensivos.
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1.
Sarmiento PE, Bono J, Barcudi R. Utilidad de las troponinas para el manejo del paciente crítico con enfermedad no cardíaca en la Unidad de Cuidados Intensivo.: Revisión narrativa. Rev Arg de Ter Int. [Internet]. 10 de noviembre de 2020 [citado 21 de diciembre de 2024];37(3). Disponible en: https://revista.sati.org.ar/index.php/MI/article/view/717
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